Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. upon oral administration, niclosamide specifically induces degradation of the androgen receptor (ar) variant v7 (ar v7) through the proteasome mediated pathway. Niclosamide, sold under the brand name niclocide among others, is a medication used to treat tapeworm infestations. this includes diphyllobothriasis , hymenolepiasis , and taeniasis .  it is not effective against other worms such as pinworms or roundworms . . Niclosamide may be taken on an empty stomach (either 1 hour before or 2 hours after a meal). however, to prevent stomach upset, it is best taken after a light meal (for example, breakfast). niclosamide tablets should be thoroughly chewed or crushed and then swallowed with a small amount of water. Niclosamide is used to treat broad or fish tapeworm, dwarf tapeworm, and beef tapeworm infections. niclosamide may also be used for other tapeworm infections as determined by your doctor. it will not work for other types of worm infections (for example, pinworms or roundworms). niclosamide works by killing tapeworms on contact. Researchers in the lab of dr. hugh d.c. smyth have released promising results of a new method to treat sars cov 2, the coronavirus that causes covid 19. the antiviral niclosamide, when incorporated with human lysozyme as a carrier molecule, shows potential as an effective covid 19 treatment when delivered directly to the airways.
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